Comparative efficacy of six Brucella vaccines in guinea-pigs.

نویسنده

  • C M Cameron
چکیده

Immunity assays in guinea-pigs based on spleen mass: body mass ratios showed that live vaccines were markedly more effective than inactivated oil adjuvant vaccines in providing protection against challenge with 5 000 virulent organisms.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran

  Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation...

متن کامل

Evaluation of Seroconversion in Guinea Pigs Following Inoculation of New Formulations of Rubella Vaccine

Background and Aims: Rubella is a contagious viral disease mostly with mild clinical symptoms and often remains undiagnosed. Rubella infection may adversely affect pregnancy, especially in the first trimester and this mother to child transmission can cause congenital rubella and may be lead to permanent disability and mortality in children. Effective rubella vaccine should be prepared using sui...

متن کامل

A comparison of virulence of intraperitoneal infection of Burkholderia mallei strains in guinea-pigs

Male guinea pigs show high susceptibility to Burkholderia mallei and have been used as animal models in glanders studies. The purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. We present here the histological changes and bacterial isolation that develop over time in guinea pigs inoculated intraperitoneally (IP) with two strain of B. mallei. Ten male guinea ...

متن کامل

Therapeutic analysis of organic acids on experimental dermatophytosis in guinea pigs

The purpose of this study was to determine the therapeutic efficacy of citric and tartaric acids on experimental dermatophytosis in guinea pigs. In this study, the susceptibility of Trichophyton mentagrophytes var. mentagrophytes to citric and tartaric acids was assessed using the macrodilution broth method. In the animal experiments, a cream consisting of the mixed acids was topically applied ...

متن کامل

STUDIES ON HEPATITIS B VACCINES

HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Gr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Onderstepoort journal of veterinary research

دوره 46 4  شماره 

صفحات  -

تاریخ انتشار 1979